| [1] |
Coughlin SS, Ekwueme DU. Breast cancer as a global health concern [J]. Cancer Epidemiol,2009,33(5):315-318.
|
| [2] |
Helme S, Perry N, Mokbel K. Screening mammography in women aged 40-49: is it time to change? [J]. Int Semin Surg Oncol,2006,3:4.
|
| [3] |
Moss SM, Cuckle H, Evans A, et al. Effect of mammographic screening from age 40 years on breast cancer mortality at 10 years’ follow-up: a randomised controlled trial[J]. Lancet,2006,368(9552):2053-2060.
|
| [4] |
Norman SA,Russell Localio A,Weber AL, et al. Protection of mammography screening against death from breast cancer in women aged 40-64 years [J]. Cancer Causes Control, 2007,18(9):909-918.
|
| [5] |
Novik KL, Nimmrich I, Genc B, et al. Epigenomics: genomewide study of methylation phenomena[J]. Curr Issues Mol Biol,2002,4(4):111-128.
|
| [6] |
蔡京伦. 表观遗传学—原理、技术与实践[M]. 上海:上海科学技术出版社,2006:169-179.
|
| [7] |
Niehrs C. Active DNA demethylation and DNA repair [J].Differentiation,2009,77(1):1-11.
|
| [8] |
Perini G, Tupler R. Altered gene silencing and human diseases[J]. Clin Genet,2006,69(1):1-7.
|
| [9] |
Schuebel KE, Chen W, Cope L, et al. Comparing the DNA hypermethylome with gene mutations in human colorectal cancer[J]. PLoS Genet,2007,3(9):1709-1723.
|
| [10] |
Ushijima T, Asada K. Aberrant DNA methylation in contrast with mutations[J]. Cancer Sci,2010,101(2):300-305.
|
| [11] |
Fang F, Turcan S, Rimner A, et al. Breast cancer methylomes establish an epigenomic foundation for metastasis[J]. Sci Transl Med,2011,3(75):75ra25.
|
| [12] |
Hoque MO, Prencipe M, Poeta ML, et al. Changes in CpG islands promoter methylation patterns during ductal breast carcinoma progression[J]. Cancer Epidemiol Biomarkers Prev,2009,18(10):2694-2700.
|
| [13] |
Lewis CM,Cler LR,Bu DW,et al. Promoter hypermethylation in benign breast epithelium in relation to predicted breast cancer risk[J]. Clin Cancer Res,2005,11(1):166-172.
|
| [14] |
Pasquali L, Bedeir A, Ringquist S, et al. Quantification of CpG island methylation in progressive breast lesions from normal to invasive carcinoma[J]. Cancer Lett,2007,257(1):136-144.
|
| [15] |
Hall JM, Lee MK, Newman B, et al. Linkage of early-onset familial breast cancer to chromosome 17q21 [J]. Science,1990,250(4988):1684-1689.
|
| [16] |
杨海捷, 王丽, 魏万里,等. 散发性乳腺癌及乳腺不典型导管增生组织BRCA1 基因启动子区甲基化分析[J]. 临床与实验病理学杂志,2008,24(2):141-145.
|
| [17] |
麻小圆, 鲁英, 杨晓燕, 等. 检测外周血中BRCA1 基因甲基化水平对乳腺癌的意义[J]. 新疆医科大学学报, 2013,36(3):325-329.
|
| [18] |
Al-Moghrabi N, Al-Qasem AJ, Aboussekhra A. Methylationrelated mutations in the BRCA1 promoter in peripheral blood cells from cancer-free women[J]. Int J Oncol,2011,39(1):129-135.
|
| [19] |
Vincent-Salomon A, Ganem-Elbaz C, Manie E, et al. X inactive-specific transcript RNA coating and genetic instability of the X chromosome in BRCA1 breast tumors[J]. Cancer Res 2007,67(11):5134-5140.
|
| [20] |
Sebova K, Zmetakova I, Bella V, et al. RASSF1A and CDH1 hypermethylation as potential epimarkers in breast cancer[J].Cancer Biomark,2012,10(1):13-26.
|
| [21] |
Lewis CM,Cler LR,Bu DW,et al. Promoter hypermethylation in benign breast epithelium in relation to predicted breast cancer risk[J]. Clin Cancer Res,2005,11(1):166-172.
|
| [22] |
Krassenstein R, Sauter E, Dulaimi E, et al. Detection of breast cancer in nipple aspirate fluid by CpG island hypermethylation[J]. Clin Cancer Res,2004,10(1):28-32.
|
| [23] |
Savitsky K, Bar-Shira A, Gilad S, et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase[J].Science,1995,268(5218):1749-1753.
|
| [24] |
Hall J. The Ataxia-telangiectasia mutated gene and breast cancer: gene expression profiles and sequence variants[J].Cancer Lett,2005,227(2):105-114.
|
| [25] |
Flanagan JM, Munoz-Alegre M, Henderson S, et al. Genebody hypermethylation of ATM in peripheral blood DNA of bilateral breast cancer patients[J]. Hum Mol Genet,2009,18(7): 1332-1342.
|
| [26] |
Brennan K, Garcias-Closas M, Orr N, et al. Intragenic ATM methylation in peripheral blood DNA as a biomarker of breast cancer risk[J]. Cancer Res,2012,72(9):2304-2313.
|
| [27] |
Lui EL, Loo WT, Zhu L, et al. DNA hypermethylation of TIMP3 gene in invasive breast ductal carcinoma [J]. Biomed Pharmacother,2005,59 Suppl 2: S363-S365.
|
| [28] |
曹新, 魏钦俊, 姜玉章, 等. 乳腺癌组织中p16 基因变异及CpG 岛甲基化状态的研究[J]. 肿瘤,2005,25(4):366-369.
|
| [29] |
Virmani AK, Rathi A, Sathyanarayana UG, et al. Aberrant methylation of the adenomatous polyposis coli (APC) gene promoter 1A in breast and lung carcinomas [J]. Clin Cancer Res,2001,7(7):1998-2004.
|
| [30] |
Jerónimo C, Costa I, Martins MC, et al. Detection of gene promoter hypermethylation in fine needle washings from breast lesions[J]. Clin Cancer Res,2003,9(9):3413-3417.
|
| [31] |
Martínez-Galán J, Torres B, Del Moral R, et al. Quantitative detection of methylated ESR1 and 14-3-3-sigma gene promoters in serum as candidate biomarkers for diagnosis of breast cancer and evaluation of treatment efficacy[J]. Cancer Biol Ther,2008,7(6):958-965.
|
| [32] |
Esteller M,Sparks A,Toyota M,et al. Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer[J].Cancer Res,2000,60(16):4366-4371.
|
| [33] |
Cowin P, Rowlands TM, Hatsell SJ. Cadherins and catenins in breast cancer[J]. Curr Opin Cell Biol,2005,17(5):499-508.
|
| [34] |
Matuschek C, Bölke E, Lammering G, et al. Methylated APC and GSTP1 genes in serum DNA correlate with the presence of circulating blood tumor cells and are associated with a more aggressive and advanced breast cancer disease[J]. Eur J Med Res,2010,15:277-286.
|
| [35] |
Radpour R, Barekati Z, Kohler C, et al. Hypermethylation of tumor suppressor genes involved in critical regulatory pathways for developing a blood-based test in breast cancer[J]. PLoS One,2011,6(1): e16080.
|
| [36] |
Tan SH, Ida H, Lau QC, et al. Detection of promoter hypermethylation in serum samples of cancer patients by methylation-specific polymerase chain reaction for tumour suppressor genes including RUNX3[J]. Oncol Rep, 2007,18(5): 1225-1230.
|
| [37] |
Evron E, Dooley WC, Umbricht CB, et al. Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR[J]. Lancet,2001,357(9265):1335-1336.
|
| [38] |
Suijkerbuijk KP, van Diest PJ, van der Wall E. Improving early breast cancer detection: focus on methylation[J]. Ann Oncol,2011,22(1):24-29.
|
| [39] |
Jones PA,Baylin SB. The fundamental role of epigenetic events in cancer [J]. Nat Rev Genet,2002,3(6):415-428.
|
| [40] |
Widschwendter M, Jones PA. DNA methylation and breast carcinogenesis [J]. Oncogene,2002,21(35):5462-5482.
|
| [41] |
Shukla S, Mirza S, Sharma G, et al. Detection of RASSF1A and RARbeta hypermethylation in serum DNA from breast cancer patients[J]. Epigenetics,2006,1(2):88-93.
|
| [42] |
Jing F, Yuping W, Yong C, et al. CpG island methylator phenotype of multigene in serum of sporadic breast carcinoma[J]. Tumour Biol,2010,31(4):321-331.
|
| [43] |
Jing F, Zhang J, Tao J, et al. Hypermethylation of tumor suppressor genes BRCA1, p16 and 14-3-3 sigma in serum of sporadic breast cancer patients[J]. Onkologie, 2007, 30(1-2):14-19.
|
| [44] |
Sharma G, Mirza S, Prasad CP, et al. Promoter hypermethylation of p16INK4A, p14ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients[J]. Life Sci,2007,80(20):1873-1881.
|